TRANS-1,2,3,6-TETRAHYDROPHTHALIC ACID DIETHYL ESTER

TRANS-1,2,3,6-TETRAHYDROPHTHALIC ACID DIETHYL ESTER - Names and Identifiers

Name	Diethyl trans-4-cyclohexene-1,2-dicarboxylate
Synonyms	Diethyl cyclohex-4-ene-1,2-dicarboxylate DIETHYL TRANS-1,2,3,6-TETRAHYDROPHTHALATE Diethyl trans-4-Cyclohexene-1,2-dicarboxylate DIETHYL TRANS-4-CYCLOHEXENE-1,2-DICARBOXYLATE Diethyl trans-4-cyclohexene-1,2-dicarboxylate trans-Diethyl cyclohex-4-ene-1,2-dicarboxylate diethyl (1S,2S)-cyclohex-4-ene-1,2-dicarboxylate 4-cyclohexene-1,2-dicarboxylic acid, diethyl ester TRANS-1,2,3,6-TETRAHYDROPHTHALIC ACID DIETHYL ESTER TRANS-4-CYCLOHEXENE-1,2-DICARBOXYLIC ACID DIETHYL ESTER trans-4-Cyclohexene-1,2-dicarboxylic Acid Diethyl EsterDiethyl trans-1,2,3,6-Tetrahydrophthalatetrans-1,2,3,6-Tetrahydrophthalic Acid Diethyl Ester
CAS	5048-50-0
InChI	InChI=1/C12H18O4/c1-3-15-11(13)9-7-5-6-8-10(9)12(14)16-4-2/h5-6,9-10H,3-4,7-8H2,1-2H3/t9-,10-/m0/s1

TRANS-1,2,3,6-TETRAHYDROPHTHALIC ACID DIETHYL ESTER - Physico-chemical Properties

Molecular Formula	C12H18O4
Molar Mass	226.27
Density	1.064
Boling Point	160-161 °C(Press: 20 Torr)
Flash Point	138.147°C
Vapor Presure	0.002mmHg at 25°C
Appearance	clear liquid
Color	Colorless to Light yellow
Storage Condition	2-8°C
Refractive Index	1.4560-1.4600
MDL	MFCD06799457

TRANS-1,2,3,6-TETRAHYDROPHTHALIC ACID DIETHYL ESTER - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany	3
HS Code	29172090

TRANS-1,2,3,6-TETRAHYDROPHTHALIC ACID DIETHYL ESTER - Introduction

Diethyl trans-4-cyclohexene-1,2-dicarboxylate(Diethyl trans-4-cyclohexene-1,2-dicarboxylate) is an organic compound with the chemical formula C14H20O4.

Nature:
Diethyl trans-4-cyclohexene-1,2-dicarboxylate is a colorless to light yellow liquid with low volatility at room temperature. It has a density of approximately 1.05 g/mL, a melting point of -25°C, and a boiling point of 295°C. It is soluble in many organic solvents, such as ethanol, ether and benzene.

Use:
Diethyl trans-4-cyclohexene-1,2-dicarboxylate is widely used in the field of organic synthesis. It can be used as a raw material for the synthesis of certain drugs in the pharmaceutical field, such as the synthetic intermediate of the antidepressant fluoxetine. In addition, it can also be used as a synthetic intermediate for fragrances, dyes and polymer compounds.

Preparation Method:
Diethyl trans-4-cyclohexene-1,2-dicarboxylate is usually prepared by esterifying diethyl tetrachloride phthalate with cyclohexene under base catalysis.

Safety Information:
Diethyl trans-4-cyclohexene-1,2-dicarboxylate is generally considered to be relatively safe under normal conditions of use. However, it is still a chemical and should comply with the relevant safety procedures. Breathing of vapors or contact with skin and eyes should be avoided. Care should be taken to use appropriate personal protective equipment, such as lab gloves and safety glasses.

Last Update：2024-04-09 20:52:54